Do You Know Diallyl Trisulfide?

Diallyl trisulfide, ATS, is a natural sulfur-containing organic compound extracted from Allium plants such as garlic. Due to its significant biological activity, it has been proven to be an important substance with both antibacterial and anti-inflammatory properties.

In the field of antibacterial

Diallyl trisulfide can exhibit good inhibitory effects on common pathogenic bacteria such as Staphylococcus aureus and Escherichia coli by disrupting the integrity of bacterial cell membranes, interfering with their metabolic enzyme activities, and other mechanisms. It even has a certain killing effect on some drug-resistant strains; At the same time, it can also inhibit the growth of fungi such as Candida albicans, playing a key role in resisting the invasion of pathogenic microorganisms.

In terms of anti-inflammatory mechanism

Diallyl trisulfide can regulate inflammation related signaling pathways, inhibit the activation of key transcription factors such as nuclear factor kappa B (NF - κ B), reduce the production and release of pro-inflammatory cytokines such as tumor necrosis factor - α (TNF - α) and interleukin-6 (IL-6), and effectively alleviate the body's inflammatory response. With these characteristics, diallyl trisulfide has not only become a hot topic in the research of antimicrobial and anti-inflammatory drugs, but also has the potential to play a greater role in the development of new anti infective and anti-inflammatory drugs, as well as in the clinical treatment of related diseases.