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What are the uses of 4,5-Dicyanoimidazole?

2024-10-02

4,5-Dicyanoimidazole is a chemical compound with the molecular formula C6H3N5. It is a white, crystalline powder that is commonly used in organic synthesis. The compound is also known as DCI and has a CAS number of 1122-28-7.
4,5-Dicyanoimidazole


What are the uses of 4,5-Dicyanoimidazole?

4,5-Dicyanoimidazole is a versatile compound and finds its use in several industries. It is used in the manufacturing of pharmaceuticals, agrochemicals, and dyes. The compound is also used as a curing agent for epoxy resins and a crosslinking agent for polymers.

What are the properties of 4,5-Dicyanoimidazole?

4,5-Dicyanoimidazole is a stable compound that can be stored for long periods. It is soluble in most organic solvents. The compound has a melting point of 220-225 °C, and its boiling point is 346.9 °C. Also, it is a weak acid, so it slightly dissolves in water.

What are the safety precautions to be taken while handling 4,5-Dicyanoimidazole?

4,5-Dicyanoimidazole is a hazardous chemical compound, and handling it requires precautions. The compound may cause skin and respiratory irritation, so it is recommended to wear gloves and a mask while handling it. The compound should be stored in a cool and dry place, away from sources of ignition.

What is the role of 4,5-Dicyanoimidazole in the pharmaceutical industry?

4,5-Dicyanoimidazole is an important intermediate in the synthesis of several drugs. It is used as a building block in the manufacture of antiviral and antifungal agents. Also, it is used in the production of kinase inhibitors and anticancer drugs.

In summary, 4,5-Dicyanoimidazole is a versatile and widely used compound in several industries. However, it requires careful handling and storage due to its hazardous nature.

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Research Papers

Lee, J.; Jang, J.; Lee, H. J.; Lim, M.; Jhon, D. Y.; Kim, D.; Cho, Y. S. (2005). "Synthesis and biological evaluation of imidazole-4,5-dicarbonitrile derivatives as antitumor agents". Journal of Medicinal Chemistry. 48 (2): 416–423. doi:10.1021/jm0492561.

Liu, C.; Qiao, X.; Yu, X.; Tian, F.; Li, Y.; Li, Z.; Ye, Y.; Ji, M.; Qi, J. (2009). "Efficient synthesis of a new intermediate of the pyrazole acaricides". Journal of Chemical Research. 2009 (1): 58–60. doi:10.3184/030823409X392982.

Rao, V. S.; Muguli, C. K.; Boja, P.; Khazi, I. M. (2008). "Superior synthesis of pharmacologically relevant imidazole-4,5-dicarbonitrile derivatives using dipolar non-classical carbocation salts". Tetrahedron Letters. 49 (45): 6474–6478. doi:10.1016/j.tetlet.2008.09.027.

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